Sinclair Method Studies
This article examines the scientific foundation behind TSM, drawing on nearly three decades of peer‑reviewed trials, neuroimaging research, and systematic reviews.
Traditionally, the path to recovery has been abstinence — quitting entirely, often with the support of meetings, rehab, or willpower alone. But what if you’re not ready to stop completely? What if your brain isn’t letting go that easily? Enter the Sinclair Method — a medically proven alternative that’s changing how we view and treat alcohol dependency.
Rethink Drink’s Trustpilot page features many verified reviews from clients who’ve experienced life-changing results. Ranging from liberation from daily drinking to newfound confidence, the feedback reflects genuine transformation through the Sinclair Method.
Endorphins are natural opioids produced by the brain that regulate pain and pleasure. When alcohol is consumed, it triggers the release of these endorphins in brain areas linked to reward, such as the nucleus accumbens and orbitofrontal cortex. This release creates feelings of euphoria and relaxation, reinforcing the urge to drink.